![]() ![]() This study also included around 900 people aged between 18 and 59 years who received either Apexxnar or Prevenar 13. It was noted that although comparable, the antibody levels with Apexxnar were lower than with Prevenar 13 for most of the serotypes included in both vaccines. One month after each vaccination, the levels of antibodies across the 2 groups were comparable for all but one of the serotypes included in Apexxnar. In one study conducted in around 3,000 people from 60 years of age, participants received either Apexxnar, or Prevenar 13 followed one month later by Pneumovax 23. Apexxnar was considered to be protective against pneumococcal disease based on the known effectiveness of Prevenar 13 and Pneumovax 23. pneumoniae (serotypes) targeted by Apexxnar. Between them, Prevenar 13 and Pneumovax 23 cover the 20 types of S. pneumoniae Pneumovax 23, a vaccine that protects against 23 types of S. pneumoniae). In 2 main studies, Apexxnar was shown to trigger immune responses that were comparable to those triggered by two other authorised pneumococcal vaccines (Prevenar 13, a vaccine that protects againstġ3 types of S. What benefits of Apexxnar have been shown in studies? This helps to protect against the disease. The immune system will then be able to produce antibodies more quickly when it comes into contact with the bacteria that have those polysaccharides on their capsules. When a person is given Apexxnar, the immune system recognises the polysaccharides in the vaccine as ‘foreign’ and makes antibodies against them. pneumoniae that can cause invasive disease and pneumonia. Apexxnar contains the polysaccharides from 20 different types of S. The vaccine is also adsorbed (fixed) onto an aluminium adjuvant (a substance to help strengthen the immune response to the vaccine). These polysaccharides have been purified, then conjugated (attached) to a carrier protein that helps the immune system to recognise them and respond in an enhanced manner. pneumoniae.Īpexxnar contains small amounts of polysaccharides (a type of sugar) extracted from the ‘capsule’ that surrounds the S. Apexxnar prepares the body to defend itself against invasive disease and pneumonia caused by S. ![]() These adults can talk with their doctor and decide, together, whether to get PCV20.Vaccines work by ‘teaching’ the immune system (the body’s natural defences) how to defend itself against a disease.
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